SubtiBank SubtiBank
Version comparison:

2017-07-13 09:45:342025-05-09 05:38:17

locus

BSU17680

BSU_17680

geneLength

837

840

outlinks

uniprot

P42326

P0CI79

outlinks

bsu

BSU17680

BSU_17680

Gene

Coordinates

1,902,219 → 1,903,058

1,902,219 1,903,058

The protein

Catalyzed reaction/ biological activity

5,10-methylenetetrahydrofolate dUMP = dihydrofolate dTMP (according to Swiss-Prot)

(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + dUMP --> 7,8-dihydrofolate + dTMP (according to UniProt)

The protein

Protein family

Bacterial-type thyA subfamily (according to Swiss-Prot)

thymidylate synthase family (with [[protein|ThyB]], according to UniProt)

The protein

Paralogous protein(s)

[[protein|ThyB]]

[[this]]

The protein

Structure

[PDB|1B02]

[PDB|1B02] [pubmed|10091656]

References

418407, 11267663

Biological materials

Mutant

BKE17680 ([[gene|thyA]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE17680 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGACTATTCATATCCTTC, downstream forward: _UP4_TAATGCTGCCTTTTTATTGT

BKK17680 ([[gene|thyA]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK17680 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGACTATTCATATCCTTC, downstream forward: _UP4_TAATGCTGCCTTTTTATTGT

References

Reviews

7574499

References

Original publications

418407, 11267663, 28700593, 10091656, 7704257, 9648749, 111614, 29150519